Size and Weight

• The two trucks are similar in size. On comparable models, they both have the same wheelbase, length, width, height and ground clearance. The F-350's curb weight of 5,815 lb. is 189.6 lb. heavier then the F-250. Other than weight, comparable Super Duty models have no size difference.
  
  

Engine

• Both F-series trucks offer a 5.4-L V8 engine as the standard option. The F-350 offers a different engine option -- a V10 engine with more power. The 6.8-L V10 offers 362 horsepower, compared with the V8's 300 horsepower. The V10 produces 457 foot-lb. of torque, compared with 365 foot-lb. from the V8. The larger engine allows the driver to pull loads more efficiently with less strain on the motor and frame.
  
  

Suspension

• The F-350 offers an upgraded suspension over the F-250. The spacers located under the rear suspension are larger than on the F-250. The rear leaf springs are also slightly larger. These features allow the F-350 to have a significantly higher gross vehicle weight rating. The F-250 is capable of towing up to 12,500 lb., whereas the F-350 can tow of up to 18,700 lb.
  
  

Price Tag

• The F-350's greater towing capacity carries a higher price tag. According to Ford's website, the F-250 had a manufacturer's suggested retail price of $28,505 at the time of publication; the F-350's price was $29,225. The prices between the two can differ greatly after the addition of optional features.