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People on all continents have used hundreds to thousands of indigenous plants for treatment of illnesses since prehistoric times.The first often accepted use of plants as healing agents was depicted in the cavern paintings discovered in the Lascaux caves in France, which have been radiocarbon-dated to between 13,000-25,000 BC. Medical herbs were found in the private aftermath of an "ice man", whose body was frozen in the Swiss Alps for more than 5,300 years. These herbs seem to have been used to treat the bugs found in his guts. Anthropology or anthropologists theorize that animals evolved a tendency to seek out bitter plant parts replying to illness.

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In the written record, the study of herbs goes back over 5,000 years to the Sumerians, who described well-established medical uses for such plants as laurel, caraway, and thyme. Traditional Egyptian drugs of one thousand B.C. Are known to have used garlic, opium, castor oil, coriander, mint, indigo, and other herbs for medication and the Old Testament also touches on herb use and cultivation, including mandrake, vetch, caraway, wheat, barley, and rye.

Many of the pharmaceuticals now available to doctors have a long history of use as herbal cures, including opium, aspirin, digitalis, and quinine. The World Health Organization ( WHO ) guesses that eighty % of the world's population currently uses herbal medication for some facet of first health care.[31] Pharmaceuticals are prohibitively costly for most of the world's population, half which which lives on less than $2 U.S. Each day. In comparison, herbal medicines can be grown from seed or gathered from nature for almost no cost. Herbal drugs is a major component in all traditional medicine systems, and a common element in Siddha, Ayurvedic, homeopathic, naturopathic, normal Chinese medicine, and Native American medicine.

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