Endoscopic Therapies for Barrett's-Associated Dysplasia
Endoscopic Therapies for Barrett's-Associated Dysplasia
The evolution of endoscopic therapies for Barrett's-associated dysplasia represents a significant landmark in gastroenterology. The safety and efficacy of EMR and RFA specifically have made a significant impact on patients who previously would have undergone esophagectomy. The past decade has seen the emergence of these endoscopic technologies and a subsequent paradigm shift in management of BE-associated dysplasia. This represents a significant step forward in esophageal cancer prevention. While prospective data demonstrating a reduction in incidence of esophageal cancer are not available, it is clear that eradication of BE-associated dysplasia is cost effective and clearly prevents cancer progression.
Expert Commentary
The evolution of endoscopic therapies for Barrett's-associated dysplasia represents a significant landmark in gastroenterology. The safety and efficacy of EMR and RFA specifically have made a significant impact on patients who previously would have undergone esophagectomy. The past decade has seen the emergence of these endoscopic technologies and a subsequent paradigm shift in management of BE-associated dysplasia. This represents a significant step forward in esophageal cancer prevention. While prospective data demonstrating a reduction in incidence of esophageal cancer are not available, it is clear that eradication of BE-associated dysplasia is cost effective and clearly prevents cancer progression.