<!-- @page { size: 21cm 29.7cm; margin: 2cm } P { margin-bottom: 0.21cm } -->
Skin tags may occur singly or multiply, and they are most often found in intertriginous areas (eg, axillae, neck, eyelids). They are also commonly located on the trunk, the groin, the abdomen, and the back. FEPs of the oral mucosa, anus, and vulvovaginal areas may be found. These lesions may be flesh colored or hyperpigmented.
Three types of acrochordons are described. Small, furrowed papules of approximately 1-2 mm in width and height are located mostly on the neck and the axillae. Single or multiple filiform lesions of approximately 2 mm in width and 5 mm in length occur elsewhere on the body. Large, pedunculated tumor or nevoid, baglike, soft fibromas can occur on the lower part of the trunk.
Pedunculated lesions may become twisted, infarcted, and fall off spontaneously. Frequent irritation seems to be an important causative factor, especially in persons who are obese. An opinion also exists that acrochordons are simply the effect of skin aging, with many factors responsible for their development.
Hormone imbalances may facilitate the development of acrochordons (eg, high levels of estrogen and progesterone during pregnancy, high levels of growth hormone in acromegaly). Epidermal growth factor and alpha tissue growth factor have also been implicated in the development of tumors such as these. Whether any infective factors initiate acrochordon growth is still not clear.
HPV types 6 and 11 DNA were found in a high percentage of skin tag biopsy samples obtained from patients. Thus, viral infection should be considered as a pathogenic cofactor. Acrochordons associated with fibrofolliculomas and trichodiscomas have been described as components of BHD syndrome, an autosomal dominant disorder.
They have been reported to accompany other neoplasms, especially tumors of the gastrointestinal tract and kidneys. Neoplasms are suggested to produce and release growth factors that cause acrochordon growth into the circulation. The results of a recent study refute the theory that an association of acrochordons and colonic polyps actually exists.
An association with type 2 diabetes mellitus has been observed. A study with acrochordon reported an incidence of 40.6% of either overt type 2 diabetes mellitus or impaired glucose tolerance. Reports exist suggesting that the mechanism is through the effect of insulin and glucose starvation. The previous study showed no correlation between the location, size, color, or number of acrochordons with impairment of glucose tolerance.
Rarely, a tick infestation may simulate a necrotic acrochordon. Metastatic melanoma may be first evident as an infarcted acrochordon. Squamous cell carcinoma may rarely be found within an acrochordon. Skin tag-like basal cell carcinomas in childhood may be a marker for basal cell nevus syndrome.
Dermatoscopic evaluation may be of value when they are suspected, although the diagnosis of a cancer is always histologic. Like warts, skin tags are classically treated by burning, or freezing the tissue with liquid nitrogen. Some doctors may opt to surgically remove skin tags. However, once surgical intervention or chemical acids are used, a scar is likely to occur in that area.
SkinTagCure represents a safe and effective alternative to these invasive procedures. It is a new all natural, certified organic topical treatment that works quickly to eliminate skin tags. Application provides rapid elimination of skin tags. Its effectiveness against skin tag is supported by published scientific studies.
SkinTagCure is formulated at maximum strength and has produced spectacular results in the elimination of skin tags in almost all known cases. Application typically causes the skin tags to safely dissolve day by day, which leads to complete elimination in 1 to 3 weeks. They may also dry up and simply flake off within the same time frame.
This high-quality product contains strictly certified organic pharmacological plant extracts, which have the proven ability to eradicate skin tags and skin tumors quickly. The extracts are harvested and distilled by hand for medicinal use. This is critical when treating any infection on the skin. To learn more, please go to http://www.bcured.net.
Skin tags may occur singly or multiply, and they are most often found in intertriginous areas (eg, axillae, neck, eyelids). They are also commonly located on the trunk, the groin, the abdomen, and the back. FEPs of the oral mucosa, anus, and vulvovaginal areas may be found. These lesions may be flesh colored or hyperpigmented.
Three types of acrochordons are described. Small, furrowed papules of approximately 1-2 mm in width and height are located mostly on the neck and the axillae. Single or multiple filiform lesions of approximately 2 mm in width and 5 mm in length occur elsewhere on the body. Large, pedunculated tumor or nevoid, baglike, soft fibromas can occur on the lower part of the trunk.
Pedunculated lesions may become twisted, infarcted, and fall off spontaneously. Frequent irritation seems to be an important causative factor, especially in persons who are obese. An opinion also exists that acrochordons are simply the effect of skin aging, with many factors responsible for their development.
Hormone imbalances may facilitate the development of acrochordons (eg, high levels of estrogen and progesterone during pregnancy, high levels of growth hormone in acromegaly). Epidermal growth factor and alpha tissue growth factor have also been implicated in the development of tumors such as these. Whether any infective factors initiate acrochordon growth is still not clear.
HPV types 6 and 11 DNA were found in a high percentage of skin tag biopsy samples obtained from patients. Thus, viral infection should be considered as a pathogenic cofactor. Acrochordons associated with fibrofolliculomas and trichodiscomas have been described as components of BHD syndrome, an autosomal dominant disorder.
They have been reported to accompany other neoplasms, especially tumors of the gastrointestinal tract and kidneys. Neoplasms are suggested to produce and release growth factors that cause acrochordon growth into the circulation. The results of a recent study refute the theory that an association of acrochordons and colonic polyps actually exists.
An association with type 2 diabetes mellitus has been observed. A study with acrochordon reported an incidence of 40.6% of either overt type 2 diabetes mellitus or impaired glucose tolerance. Reports exist suggesting that the mechanism is through the effect of insulin and glucose starvation. The previous study showed no correlation between the location, size, color, or number of acrochordons with impairment of glucose tolerance.
Rarely, a tick infestation may simulate a necrotic acrochordon. Metastatic melanoma may be first evident as an infarcted acrochordon. Squamous cell carcinoma may rarely be found within an acrochordon. Skin tag-like basal cell carcinomas in childhood may be a marker for basal cell nevus syndrome.
Dermatoscopic evaluation may be of value when they are suspected, although the diagnosis of a cancer is always histologic. Like warts, skin tags are classically treated by burning, or freezing the tissue with liquid nitrogen. Some doctors may opt to surgically remove skin tags. However, once surgical intervention or chemical acids are used, a scar is likely to occur in that area.
SkinTagCure represents a safe and effective alternative to these invasive procedures. It is a new all natural, certified organic topical treatment that works quickly to eliminate skin tags. Application provides rapid elimination of skin tags. Its effectiveness against skin tag is supported by published scientific studies.
SkinTagCure is formulated at maximum strength and has produced spectacular results in the elimination of skin tags in almost all known cases. Application typically causes the skin tags to safely dissolve day by day, which leads to complete elimination in 1 to 3 weeks. They may also dry up and simply flake off within the same time frame.
This high-quality product contains strictly certified organic pharmacological plant extracts, which have the proven ability to eradicate skin tags and skin tumors quickly. The extracts are harvested and distilled by hand for medicinal use. This is critical when treating any infection on the skin. To learn more, please go to http://www.bcured.net.